Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma
Status:
Completed
Trial end date:
2019-04-01
Target enrollment:
Participant gender:
Summary
Photon beam radiation is the standard type of radiation used to treat nasopharyngeal
carcinoma. Photon beam radiation enters the body and passes through healthy tissue,
encounters the tumor and leaves the body through healthy tissue. Proton beam radiation has
been shown to have the same effect on tumors as photon beam radiation but it enters the body,
passes through healthy tissue, and encounters the tumor but then stops. This means less
healthy tissue is affected by proton beam treatment than by photon beam treatment. The
purpose of this study is to determine the effectiveness of proton beam radiation in treating
nasopharyngeal cancer and reducing the acute and long-term side effects from the treatment.
This study will also test to see if the sparing of the healthy tissue can improve quality of
life
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
Brigham and Women's Hospital Dana-Farber Cancer Institute