Protracted Mixture of Local Anesthetics for Major Foot and Ankle Surgery

• Status: Completed
• Trial end date: 2016-07-01
• Target enrollment: 0
• Participant gender: All

Summary

To extend the duration of peripheral nerve blockade after major foot and ankle surgery the investigators randomize the postoperative treatment with either perineurial sciatic nerve blocks with 0.5% Bupivacaine-Epinephrine with or without Dexamethasone.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rasmus Wulff Hauritz
• Collaborator: Aarhus University Hospital
• Treatments: Anesthetics; Anesthetics, Local; BB 1101; Bupivacaine; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Epinephrine; Epinephryl borate; Racepinephrine

Criteria

Inclusion Criteria:

• age > 17

• scheduled major foot and ankle surgery

• written informed consent

• fertile women in anti conceptive treatment

• fertile women not in anti conceptive treatment, but with negative urin-HCG on day of surgery

Exclusion Criteria:

• patients not able to understand or cooperate

• allergies to medicines involved

• daily buse of steroids

• daily use of opioids