Pupillary Dilation After Incremental Tetanic Stimulations Under Ketamine Sedation
Status:
Completed
Trial end date:
2013-04-01
Target enrollment:
Participant gender:
Summary
The aim of the study was to describe the relationship between the intensity of a standardized
tetanic stimulation and the associated reflex pupillary dilation in patients under ketamine
sedation.
After an intravenous bolus of 1 mg/kg of ketamine, tetanic stimulations were performed every
minute at increasing intensities of 10, 20, 30, 40 and 60 milliamps (similar to the
stimulations of neuromuscular blocking agents monitoring). Pupillary diameter was measured
before and after each stimulation.