Pupillometry - Future of Objective Pain Reaction Measurement While Unconscious

• Status: Completed
• Trial end date: 2019-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to assess the usefulness of pupillometry as a nociceptive indicator during elective orotracheal intubation in patients given intravenous lignocaine pre-intubation as compared to a placebo pre-intubation.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Warmia and Mazury
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Physical State 1 or 2 of the American Society of Anesthesiology (ASA)

• Electively scheduled for surgery requiring general anesthesia

• Age >18 years

Exclusion Criteria:

• Difficult airway

• Unanticipated difficult airway based on the previous history of difficult intubation

• Urgently scheduled for surgery requiring general anesthesia

• Ophthalmologic pathology precluding pupillometry, ex. Horner's syndrome, Sjogrens syndrome

• Anisocoria

• History of opioid abuse

• Subjects who are or may be pregnant

• Unable to converse in Polish

• History of psychiatric/cognitive disease

• Patients who do not give informed consent

• Patients with contraindications or history of hypersensitivity to lidocaine

• Patients with coronary ischemic disease

• Patients with atrioventricular block at any grade

• Patients with diagnosed cardiac arrhythmias

• Patients with heart failure

• Patients who are taking drugs influencing the pupil size

• Patients with pacemaker

• Patients younger than 18 years of age

• History of chronic pain, chronic opioid use (> 3 months)