Overview

Pyronaridine in Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)

Status:
Not yet recruiting
Trial end date:
2023-07-01
Target enrollment:
Participant gender:
Summary
A Phase 2a clinical trial on up to n=200 male and female subjects 18 years and over who were diagnosed with acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL). Subjects are randomised in approximately a 1:1 ratio to receive standard of care treatment plus either pyronaridine (PND) or placebo. Quality of life parameters are measured. Visits include physical examinations, and blood draws for complete blood count with differential (CBC) and complete metabolic panel (CMP). Survival of subjects is tracked in Year 2.
Phase:
Phase 2
Details
Lead Sponsor:
Armaceutica, Inc.
Collaborators:
African Center for Cancer Research and End of Life Care (ACREOL), Rwanda
Dalal Jamm Hospital, Dakar, Senegal
Groupe de Recherche Action en Santé (GRAS), Burkina Faso
Ifakara Health Research and Development Centre
SingMed, Cambodia and Singapore
Uganda Cancer Institute
University of Ghana
Treatments:
Pyronaridine