Overview

QUILT-3.090: NANT Squamous Cell Carcinoma (SCC) Vaccine: Subjects With SCC Who Have Progressed

Status:
Active, not recruiting
Trial end date:
2021-04-01
Target enrollment:
Participant gender:
Summary
This is a phase 1b/2 study to evaluate the safety and efficacy of metronomic combination therapy in subjects with SCC who have progressed on or after previous platinum-based chemotherapy and anti-PD-1/PD-L1 therapy. Phase 2 will be based on Simon's two-stage optimal design.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
ImmunityBio, Inc.
Treatments:
Avelumab
Bevacizumab
Capecitabine
Cetuximab
Cyclophosphamide
Fluorouracil
Leucovorin
Necitumumab
Paclitaxel