Quantitative D-dimer Level and Anticoagulant Therapy in Idiopathic Intracranial Hypertension

• Status: Completed
• Trial end date: 2018-08-02
• Target enrollment: 0
• Participant gender: All

Summary

Idiopathic intracranial hypertension (IIH) is a syndrome characterized by elevated intracranial pressure (ICP) of unknown etiology.

The investigators aim to study the quantitative D-dimer level and the role of anticoagulant therapy in the absence of occlusive sinus thrombosis in IIH patients.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Fayoum University
• Treatments: Acetazolamide; Anticoagulants; Fibrin fragment D

Criteria

Inclusion Criteria:

• IIH patients of both sexes fulfilling the modified Dandy criteria

Exclusion Criteria:

• disturbed conscious level, focal neurological signs, seizures, cerebral venous sinus thrombosis or stenosis, deep venous thrombosis or pulmonary embolism, malignancy, and acute nephritic syndrome.

• Patients with signs of disseminated intravascular coagulopathy and septic sinus thrombosis

• patients with a history of cerebral granuloma or infection, cerebrovascular stroke, head trauma or surgery.

• pregnant females or those who terminated their pregnancy in the last four weeks were also excluded.