Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy
Status:
Completed
Trial end date:
2009-06-01
Target enrollment:
Participant gender:
Summary
A) for the treatment of uncomplicated malaria during second and third trimester pregnancy to
oral Quinine hydrochloride. The PCR-corrected adequate clinical and parasitological response
(ACPR) on day 42 is considered as the primary efficacy criterion. Newborns will be followed
for growth and development indicators.
Phase:
Phase 4
Details
Lead Sponsor:
Epicentre
Collaborators:
Medecins Sans Frontieres, Netherlands Shoklo Malaria Research Unit Sholklo Malaria Research Unit University of Cape Town
Treatments:
Artemether Artemether-lumefantrine combination Artemether, Lumefantrine Drug Combination Artemisinins Lumefantrine Quinine