Quinolone Prophylaxis for the Prevention of BK Virus Infection in Kidney Transplantation: A Pilot Study
Status:
Completed
Trial end date:
2014-10-01
Target enrollment:
Participant gender:
Summary
Primary Research Questions:
Efficacy, safety and feasibility of a 3-month course of levofloxacin in a pilot study will be
assessed.
1. Under efficacy, this pilot will determine whether levofloxacin can decrease the
incidence of BK viruria and peak urine BK viral load.
2. Under safety, this pilot will determine the incidence of adverse events with
levofloxacin.
3. Under feasibility, this pilot will determine the number of kidney transplant patients
randomized over an eight month enrolment period, adherence to the levofloxacin and
frequency of patient drop-out and loss to follow-up
Phase:
Phase 4
Details
Lead Sponsor:
Ottawa Hospital Research Institute
Collaborators:
Canadian Institutes of Health Research (CIHR) Dalhousie University London Health Sciences Centre McGill University Health Center McGill University Health Centre/Research Institute of the McGill University Health Centre St. Joseph's Healthcare Hamilton St. Michael's Hospital, Toronto St. Paul's Hospital, Canada Unity Health Toronto University Health Network, Toronto University of Alberta University of Manitoba Vancouver General Hospital