Qvar Versus Clenil, a General Practice Research Database Study

• Status: Completed
• Trial end date: 2010-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will compare the absolute and relative effectiveness of asthma management in patients on inhaled corticosteroid (ICS) maintenance therapy as either extra-fine-particle or larger-particle formulation beclomethasone dipropionate (BDP) via metered-dose inhalers (MDIs) using the propellant hydrofluoroalkane propellant (HFA-BDP), namely Qvar® MDI compared with Clenil® MDI.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Research in Real-Life Ltd
• Collaborators: Teva Branded Pharmaceutical Products R&D, Inc.; Teva Pharmaceutical Industries
• Treatments: Beclomethasone

Criteria

Inclusion Criteria:

• Aged: 4-80 years

• Paediatric cohort (aged 4-11 years), and

• Adult cohort (aged 12-80 years )

• Evidence of asthma and current asthma therapy:

• All cohorts (IPDI, IPDS, IPDA):

• a diagnostic code for asthma, and / or *≥2 prescriptions for asthma at different points in time during the prior year and/or IPDI only: ≥2 prescriptions for asthma therapies during the outcome year, including ≥1 ICS prescription in addition to that received at IPD

IPDA and IPDS only:

• 1 ICS prescription in the baseline year, and

• 1 other asthma prescription during the baseline year.

*Evidence of "current therapy":

• 2 prescription for ICS during the outcome year (i.e. ≥1 prescription in addition to the prescription at index date

• Have at least one year of up-to-standard (UTS) baseline data (prior to the IPD) and at least one year of UTS outcome data (following the IPD).

Exclusion Criteria:

• Had a COPD read code at any time; and/or

• Had any chronic respiratory disease, except asthma, at any time; and/or

• Patients on maintenance oral steroids during baseline year

• Received a combination inhaler in addition to a separate ICS inhaler in the baseline year; and/or

• Received ICS therapy during baseline year via DPI (IPDA and IPDS cohorts only).

• If they received multiple ICS prescriptions on the same day at IPD or immediately before