R-(-)-Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer
Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
This phase II trial is studying how well giving gossypol together with androgen ablation
therapy works in treating patients with newly diagnosed metastatic prostate cancer. Gossypol
may stop the growth of tumor cells by blocking blood flow to the tumor. Androgens can cause
the growth of prostate tumor cells. Luteinizing hormone-releasing hormone agonists and drugs,
such as bicalutamide, may lessen the amount of androgens made by the body. Giving gossypol
together with androgen ablation therapy may be an effective treatment for prostate cancer