RATTRAP: Infliximab Versus Rituximab in Systemic Necrotizing Vasculitides

• Status: Completed
• Trial end date: 2007-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare a 2 immunosuppressant regimen for the treatment of relapsing or refractory necrotizing antineutrophil cytoplasmic antibody (ANCA) associated vasculitides.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assistance Publique - Hôpitaux de Paris
• Treatments: Immunosuppressive Agents; Infliximab; Rituximab

Criteria

Inclusion Criteria:

• Systemic ANCA positive (+) vasculitides

• Relapsing or refractory vasculitides, resistant to corticosteroids and reference immunosuppressant therapies

• Age >18 years old

• Written informed consent

Exclusion Criteria:

• Newly diagnosed patient

• Patient that had never received an immunosuppressant before to treat his/her vasculitis

• Malignancy

• Pregnancy