Overview

RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC

Status:
Not yet recruiting
Trial end date:
2028-03-19
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to determine the rate of local regional control at 2 years when using de-intensified chemoradiotherapy (CRT) in patients with Human Papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HNSCC). Local regional control means no recurrence of the cancer in the head or neck area. Study subjects will be enrolled into 4 groups. Group/treatment will be based on a number of factors, including smoking and drinking history.
Phase:
Phase 2
Details
Lead Sponsor:
Icahn School of Medicine at Mount Sinai
Treatments:
Carboplatin
Cisplatin