RCT Comparing Methadone and Buprenorphine in Pregnant Women
Status:
Completed
Trial end date:
2010-06-01
Target enrollment:
Participant gender:
Summary
Children born to women who abuse drugs have a high risk of being born with birth defects and
developmental problems. Methadone is a drug that is commonly used for treating opioid
dependence. However, its use by a pregnant woman can cause severe withdrawal symptoms in a
newborn because of the prenatal exposure. The purpose of this study is to evaluate the
effectiveness of buprenorphine, another drug, versus methadone in reducing withdrawal
symptoms in children born to opioid-dependent women.