RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil
Status:
Completed
Trial end date:
2006-12-01
Target enrollment:
Participant gender:
Summary
The perinatal morbidity and mortality rates for Brazil are five to ten-fold higher than those
reported for upper income countries. This study tests the likelihood that the joint
administration of antioxidants vitamin C (1000 mg) and vitamin E (400 IU) will reduce the
incidence of preeclampsia among chronically hypertensive pregnant patients and patients with
a past history of preeclampsia/eclampsia.
Phase:
Phase 3
Details
Lead Sponsor:
NICHD Global Network for Women's and Children's Health
Collaborators:
Bill and Melinda Gates Foundation Faculdade de Medicina de Botucatu, UNESP, Botucatu, Brasil Feculdade de Medicina da Universidade de Sao Paulo - Brasil Fogarty International Center of the National Institute of Health Global Network for Women's and Children's Health Research Hospital de Clinicas de Porto Alegre John E. Fogarty International Center (FIC) National Cancer Institute (NCI) National Center for Complementary and Integrative Health (NCCIH) National Institute of Dental and Craniofacial Research (NIDCR) RTI International Universidade Federal de Pernambuco University of Campinas, Brazil University of Cincinnati