RCT of CBT Combined With D-Cycloserine for Treating PTSD

• Status: Unknown status
• Trial end date: 2008-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate if the effectiveness of cognitive-behavioral therapy for post-traumatic stress disorder can be increased by combining it with D-cycloserine (TCC/D-cycloserine) by comparing with a placebo (TCC/placebo).

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Université de Montréal
• Collaborators: Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal; Centre de recherche Fernand-Seguin, Hôpital Louis-H. Lafontaine
• Treatments: Cycloserine

Criteria

Inclusion Criteria:

• Clinical diagnosis of PTSD

• No other Axix I disorder of higher intensity than PTSD

• Accept not to start a psychopharmacological treatment before and during the participation to the project

Exclusion Criteria:

• Substance abuse

• Psychotic episodes (past or current)

• Bipolar disorder

• Organic caused mental disorder

• Intellectual deficiency

• Pregnant or breast-feeding woman

• Épilepsy