RCT of SPG Blocks for Post-dural Headache

• Status: Enrolling by invitation
• Trial end date: 2021-06-30
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of the study is to assess the effectiveness of the SPG block with lidocaine vs. SPG block with placebo on preventing the need for EBP in women who develop PDPH after accidental dural puncture during placement of LEA for labor.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Utah
• Collaborators: Duke University; Harvard University; Mayo Clinic; University of California, San Francisco; University of Colorado, Denver
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Females

• age 18-50

• Post Dural Puncture Headache after documented accidental dural puncture during placement of LEA for labor and no better explanation for headache

• onset of HA within 72 hours of delivery.

Exclusion Criteria:

• true allergy to local anesthesia

• Hereditary Hemorrhagic Telangiectasia

• inability to understand pain scores and other questionnaires

• inability to speak English

• contraindication to acetaminophen or NSAIDs

• temperature >38.5 C

• prior Epidural Blood Patch done for this headache