Overview

REDucing Hot FLASHes in Women Using Endocrine Therapy.

Status:
Not yet recruiting
Trial end date:
2029-01-01
Target enrollment:
Participant gender:
Summary
The goal of this randomized intrapatient cross-over study is to assess the efficacy of oxybutynin versus venlafaxine in reducing hot flashes in women using endocrine therapy after breast cancer. The objectives it aims to answer are: - To assess the efficacy of oxybutynin versus venlafaxine in reducing hot flashes in women using endocrine therapy after breast cancer - To assess side effects of oxybutynin versus venlafaxine. - To assess the personal preference of women for oxybutynin versus venlafaxine in reducing hot flashes. - To assess quality of life of women when reducing hot flashes in women using endocrine therapy after breast cancer. Participants will fill-out a patient diary during 15 weeks total on a daily basis and receive an (online) questionnaire three times total. Researchers will compare two groups (venlafaxine group versus oxubutynine group) to assess its efficacy concerning hot flashes.
Phase:
Phase 3
Details
Lead Sponsor:
Reinier de Graaf Groep
Treatments:
Oxybutynin
Venlafaxine Hydrochloride