RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION
Status:
Recruiting
Trial end date:
2025-04-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to propose for implementation and evaluate the
effectiveness of xenon sedation for the relief of psychoemotional stress disorder before the
operation of refractive laser vision correction patients with high anxiety and stress
instability who underwent xenon analgosedation before refractive laser vision correction. The
main question[s] it aims to answer are:
1. To develop a method of xenon sedation in patients with a high level of psychoemotional
stress before surgery - refractive laser vision correction.
2. To evaluate the effect of inhaled xenon anesthesia in a sub-narcotic dose on the
duration of surgery, satisfaction of surgeons and patients with anesthesia, the level of
postoperative pain in patients in comparison with anxiolytics.
The following will be studied: the level of preoperative anxiety, the dynamics of glycemia
and blood cortisol levels, heart rate variability, electrical microamplitudes of the ECG
signal, the anti-stress and analgesic effect of xenon.
If there is a comparison group: the researchers will compare [the group with xenon sedation
and the control group] to see if there is [an anti-stress effect of xenon in patients before
laser vision correction].
Phase:
Early Phase 1
Details
Lead Sponsor:
The S.N. Fyodorov Eye Microsurgery State Institution