Radiation Therapy, Mitomycin, and Either Fluorouracil or Cisplatin in Treating Patients With Locally Advanced Anal Cancer
Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as mitomycin, fluorouracil, and cisplatin, use
different ways to stop tumor cells from dividing so they stop growing or die. Combining
radiation therapy with chemotherapy may kill more tumor cells. It is not yet known whether
radiation therapy and mitomycin are more effective when combined with fluorouracil or with
cisplatin in treating anal cancer .
PURPOSE: This randomized phase II/III trial is studying how well giving radiation therapy and
mitomycin together with fluorouracil works compared to radiation therapy, mitomycin, and
cisplatin in treating patients with locally advanced anal cancer.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
European Organisation for Research and Treatment of Cancer - EORTC