Radiation Therapy Plus Celecoxib, Fluorouracil, and Cisplatin in Patients With Locally Advanced Cervical Cancer
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in
chemotherapy use different ways to stop tumor cells from dividing so they stop growing or
die. Giving radiation therapy in different ways and combining it with chemotherapy may kill
more tumor cells. Celecoxib may slow the growth of cervical cancer by stopping blood flow to
the tumor.
PURPOSE: Phase I/II trial to study the effectiveness of radiation therapy plus celecoxib,
fluorouracil, and cisplatin in treating patients who have locally advanced cervical cancer.