Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high energy x-rays to damage tumor cells. Drugs used in
chemotherapy use different ways to stop tumor cells from dividing so they stop growing or
die. Combining radiation therapy with chemotherapy may kill more tumor cells. It is not yet
known which chemotherapy regimen is more effective when combined with radiation therapy for
treating medulloblastoma.
PURPOSE: Randomized phase III trial to compare two combination chemotherapy treatments plus
radiation therapy in treating children with newly diagnosed medulloblastoma.
Phase:
Phase 3
Details
Lead Sponsor:
Children's Oncology Group
Collaborators:
National Cancer Institute (NCI) Pediatric Oncology Group