Radiation Therapy, Temozolomide, Tamoxifen, and Carboplatin in Treating Patients With Malignant Gliomas
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in
chemotherapy, such as temozolomide and carboplatin, work in different ways to stop the growth
of tumor cells, either by killing the cells or by stopping them from dividing. Tamoxifen may
make tumor cells more sensitive to radiation therapy and chemotherapy. Giving radiation
therapy together with temozolomide, tamoxifen, and carboplatin may kill more tumor cells.
PURPOSE: This phase II trial is studying the side effects and how well giving radiation
therapy together with temozolomide, tamoxifen, and carboplatin works in treating patients
with malignant gliomas.
Phase:
Phase 2
Details
Lead Sponsor:
San Diego Pacific Oncology & Hematology Associates