Radiation Therapy, Temozolomide, and Erlotinib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in
chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells,
either by killing the cells or by stopping them from dividing. Erlotinib may stop the growth
of tumor cells by blocking some of the enzymes needed for cell growth. Giving radiation
therapy together with temozolomide and erlotinib after surgery may kill any remaining tumor
cells.
PURPOSE: This phase II trial is studying how well giving radiation therapy together with
temozolomide and erlotinib works in treating patients with newly diagnosed glioblastoma
multiforme.