Radiation Therapy With or Without Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer
Status:
Completed
Trial end date:
2012-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in
chemotherapy such as fluorouracil and mitomycin use different ways to stop tumor cells from
dividing so they stop growing or die. Fluorouracil and mitomycin may make the tumor cells
more sensitive to radiation therapy. It is not yet known if radiation therapy is more
effective with or without chemotherapy in treating bladder cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy to all
or part of the bladder with or without chemotherapy in treating patients who have stage II or
stage III bladder cancer.