Radiation Therapy or Combination Chemotherapy in Treating Young Patients With Hodgkin's Lymphoma

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

RATIONALE: Radiation therapy uses high-energy x-rays to kill cancer cells. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells.

PURPOSE: This clinical trial is studying how well radiation therapy or combination chemotherapy work in treating young patients with Hodgkin's lymphoma.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Cancer and Leukaemia Group
• Treatments: Bleomycin; Chlorambucil; Dacarbazine; Doxorubicin; Liposomal doxorubicin; Prednisolone; Procarbazine; Vinblastine; Vincristine

Criteria

DISEASE CHARACTERISTICS:

• Histologically confirmed childhood Hodgkin's lymphoma by lymph node biopsy

• Any stage disease

• Patients with bilateral upper cervical disease with no evidence of supraclavicular, thoracic inlet, or Waldeyers ring involvement are treated as having stage I disease

PATIENT CHARACTERISTICS:

• Platelet count > 100,000/mm^3

• Absolute neutrophil count > 1,000/mm^3

PRIOR CONCURRENT THERAPY:

• Not specified