Overview

Radiation and Immune Checkpoints Blockade in Metastatic NSCLC (BMS # CA209-632)

Status:
Recruiting
Trial end date:
2022-12-30
Target enrollment:
Participant gender:
Summary
NSCLC patients with metastatic disease who have failed at least one prior treatment and have a minimum of two metastatic lesions (at least one measurable), are eligible if they have an ECOG Performance Status of 0-1. Patients will receive on Day 1, ipilimumab (every 6 weeks) concurrently with radiation (6Gy x 5 fractions). Nivolumab (every 2 weeks) will be given in addition to ipilimumab on day 22.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Weill Medical College of Cornell University
Collaborator:
Bristol-Myers Squibb
Treatments:
Ipilimumab
Nivolumab