Radiotherapy Alone Versus Concurrent Chemoradiation in Low Risk NK/T-cell Lymphoma

• Status: Terminated
• Trial end date: 2017-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to prove the superiority of concurrent chemoradiation compared with radiotherapy alone in patients with low risk NK/T-cell lymphoma.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fudan University
• Treatments: Methotrexate

Criteria

Inclusion Criteria:

• Age range 18-75 years old

• Histological confirmed, previously untreated stage IE nasal NK/T cell lymphoma without following risk factors including local invasion, B symptoms and high LDH level

• ECOG performance status 0-1

• Life expectancy of more than 3 months

• Adequate bone marrow and organ functions

Exclusion Criteria:

• non-nasal NK/T-cell lymphoma

• Prior exposure of methotrexate

• With third space effusion

• Pregnant or lactating women

• Serious uncontrolled diseases and intercurrent infection

• History of other malignancies except cured basal cell carcinoma of skin and carcinoma in-situ of uterine cervix