Radiotherapy for Malignant Astrocytomas in the Elderly

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

A randomized trial comparing radiotherapy with supportive care in patients aged 70 years or older with newly diagnosed, histologically confirmed anaplastic astrocytoma or glioblastoma, and a Karnofsky performance status > 70.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Criteria

Inclusion Criteria:

• Glioblastoma and anaplastic astrocytoma, supratentorial, histologically confirmed

• Brain CT scan or MRI within 28 days before surgery

• Age: 70 years or older

• Karnofsky performance status, 70 or more.

• Life expectancy over 12 weeks

• Informed consent

Exclusion Criteria:

• Brain radiotherapy

• Chemotherapy

• Severe systemic disease