Randomised Controlled Study of Popofol Versus Midazolam as Sedation in Endoscopy With Advanced Liver Disease.
Status:
Unknown status
Trial end date:
2018-04-01
Target enrollment:
Participant gender:
Summary
Gastrointestinal endoscopy is a frequent procedure in the patients with advanced liver
disease. It requires variable degree of sedation ranging from minimal sedation to general
anesthesia aiming for relieving pain, anxiety, and bad memories of the procedure.
In conscious sedation, patients are able to make purposeful responses to auditory and tactile
clues, with maintenance of ventilatory and circulatory stability. while, in deep sedation,
patients respond only to painful stimuli, and airway support is frequently required. At the
level of general anesthesia, patients are unresponsive, and airway support is mandatory.