Randomised Trial Comparing Iron Supplementation Versus Placebo in the Treatment of Anaemia After Hip Fracture
Status:
Completed
Trial end date:
2009-08-01
Target enrollment:
Participant gender:
Summary
At present our current practice is to provide a course of oral iron therapy for those
patients with a post-operative haemoglobin which is below normal, but not severe enough to
require a blood transfusion. Such a practice is not without side effects from the iron
tablets, namely ingestion, nausea, diarrhoea, constipation. There is little evidence in the
literature to support the current practice of using iron, with only one small randomised
trial suggesting such therapy is unnecessary. We propose to recruit 300 patients recovering
from a hip fracture with a post-operative haemoglobin below 11g/l. For those patients willing
to enter the study, half will be given oral iron therapy (ferrous sulphate 200mg twice daily)
for one month. The haemoglobin will be checked when the patients attends the hip fracture
clinic at 6 weeks after discharge.
Phase:
Phase 3
Details
Lead Sponsor:
Peterborough and Stamford Hospitals NHS Foundation Trust