Randomized Assessment of Antibiotic Prophylaxis Prior to Port Placement

• Status: Not yet recruiting
• Trial end date: 2027-12-01
• Target enrollment: 0
• Participant gender: All

Summary

A randomized, double blind, placebo-controlled clinical trial assessing the utility of antibiotic prophylaxis prior to Totally Implanted Venous Access Device (TIVAD) insertion.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dartmouth-Hitchcock Medical Center
• Treatments: Cefazolin

Criteria

Inclusion Criteria:

• Adult patients requiring TIVAD insertion for long-term central venous access

• Patients able to give informed consent to participate in the study.

Exclusion Criteria:

• taking long-term antibiotics

• unable to give consent to participate in the study

• Patients that have a known infection at time of the procedure (as documented in e-DH).

• Patients with a planned surgical procedure within 30 days of initial TIVAD insertion.

• Patients that are currently on antibiotics or have received antibiotics within the last week.

• Patients with allergies to cefazolin.

• Patients with an absolute neutrophil count of less than 500/mm3

• Women who are pregnant.