Randomized Clinical Trial of Two Different Initial Growth Hormone Doses in Children
Status:
Recruiting
Trial end date:
2025-12-10
Target enrollment:
Participant gender:
Summary
A prospective, randomized, open-label single-blinded study of 50 subjects with growth hormone
deficiency, ages 5 to 15 years in which 25 subjects will initiate rhGH therapy at
0.3mg/kg/week and the remaining 25 subjects will initiate their rhGH treatment at 0.2
mg/kg/week for the first 12 months of treatment. Safety parameters, height velocity, and
adult height prediction by bone age determination will be assessed at 4-month intervals for 1
year following the initiation of rhGH therapy.