Randomized Control Trial of a Topical Anesthetic to Evaluate Pain and Anxiety During Venipuncture

• Status: Completed
• Trial end date: 2008-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the amount of anxiety and pain felt by children during procedures that require a needle stick after using a topical anesthetic or placebo cream.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Jenny Boucher, PharmD
• Treatments: Anesthetics; Anesthetics, Local; Lidocaine

Criteria

Inclusion Criteria:

• children ages 5-18 years of age

• treated as an inpatient or outpatient at Lehigh Valley Hospital within the past 24 hours

• venipuncture order, and that order is their initial venipuncture order (required within 30 mins)

Exclusion Criteria:

• known allergy to EMLA, LMX4 or any of their ingredients

• known sensitivities to local anesthetics of the amide type, lidocaine or prilocaine

• G6PD deficiency

• methemoglobinemia or concomitant administration of methemoglobin-inducing agent

• brain injured or disoriented (Glasgow Coma Scale <15)

• cognitively impaired (Mini Mental Status Exam <28)

• active skin conditions at venipuncture site including frequent rashes, eczema or unexplained bruising