Randomized Controlled Trial of Endoscopic Dilation: Triamcinolone Injection

• Status: Active, not recruiting
• Trial end date: 0000-00-00
• Target enrollment: 10
• Participant gender: Both

Summary

The purpose of this pilot study is to find out if adding triamcinolone (steroid) injection at the participant's initial esophagogastroduodenoscopy (EGD) procedure will improve the opening of their esophagus and decrease the need for repeat dilations.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: H. Lee Moffitt Cancer Center and Research Institute
• Treatments: Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide
• Last Updated: 2016-09-13

Criteria

Inclusion Criteria:

• Patients who present for EGD with dilation for dysphagia symptoms thought secondary to either radiation-induced stricture or anastomotic stricture based on history

Exclusion Criteria:

• Inability to consent for the procedure

• Known coagulopathy [International Normalized Ratio (INR) >1.5, Platelets <75 K]

• Endoscopic finding of a stricture that is not caused by either radiation or anastomotic narrowing

• Nasopharyngeal strictures