Overview

Randomized Controlled Trials of the Effects of Decadron on Swallowing, Airway, and Arthrodesis

Status:
Unknown status
Trial end date:
2016-11-01
Target enrollment:
Participant gender:
Summary
Anterior cervical discectomy and fusion with or without decompression is a well-established surgical treatment for spine patients with the appropriate indications. Anterior approach involves some retraction that affect the midline structures of the anterior neck. Irritation and swelling may result, leading to postoperative dysphagia and the less common but critically important occurrence of postoperative airway compromise. Steroids given intraoperatively may reduce the incidence of these adverse outcomes by reducing the degree of swelling within the anterior neck subsequent to local surgical tissue trauma. The investigators hypothesize that the use of steroids intraoperatively provides a significant benefit to the patient, in terms of reduced incidence of dysphagia and airway compromise.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Albany Medical College
Treatments:
BB 1101
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate