Randomized Phase III Trial of Surgery Alone or Surgery Plus Preoperative Gemcitabine-Cisplatin in Early Stages NSCLC
Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
Preoperative chemotherapy is considered to play a role in early stage non small cell lung
cancer (NSCLC) .The use of preoperative Cisplatin/Gemcitabine chemotherapy has proven
feasible and without excessive morbidity or mortality in the Phase II setting. The aim of the
present Phase III study is to determine whether 3 cycles of preoperative chemotherapy with
Cisplatin/Gemcitabine improves progression free survival of NSCLC patients versus surgery
alone. Postoperative chemotherapy will not be utilized in this Phase III trial.