Overview

Randomized Placebo Controlled Trial of IVIg in Glycine Receptor Antibody Positive Stiff-person Syndrome

Status:
Withdrawn
Trial end date:
2019-04-26
Target enrollment:
Participant gender:
Summary
This is a randomized double-blind controlled trial of intravenous immunoglobulin (IVIg) for glycine receptor antibody positive (GlyRα1) antibody Stiff Person Syndrome (SPS) spectrum disorders. Adult patients will be enrolled over the course of 36 months. Study duration per patient will be 11 weeks. Total study duration will be 39 months. All treatment and study visits will occur at Mayo Clinic in Rochester, MN.
Phase:
Phase 3
Details
Lead Sponsor:
Mayo Clinic
Collaborators:
Grifols Biologicals Inc.
Grifols Biologicals, LLC
Treatments:
Antibodies
gamma-Globulins
Glycine
Immunoglobulins
Immunoglobulins, Intravenous
Rho(D) Immune Globulin