Randomized, Placebo-controlled, Double-blind Study of 2LHERP® in Orofacial Herpes Infections.

• Status: Recruiting
• Trial end date: 2023-03-09
• Target enrollment: 0
• Participant gender: All

Summary

Herpes simplex virus (HSV) infection is very common, as most people will experience herpetic infection during their lifetime. The most common manifestation of HSV infection is sores which may appear at any age.

No specific antiviral therapy is available to totally cure herpetic infections and today, there is no treatment that allows the definitive eradication of the virus.

The 2LHERP® has been available for more than 20 years, and has received a marketing authorization in Belgium by the FAMHP. It is used as an immune regulator in the treatment of herpetic infections. Since 2LHERP® has been made available, clinical observational data collected on treated patients have shown the beneficial effect on the disappearance of herpetic recurrences.

The purpose of this placebo-controlled trial is to evaluate the efficacy of 2LHERP® on the treatment of herpetic infections in adults.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Labo'Life

Criteria

Inclusion Criteria:

• Man or woman aged 18-80 years,

• Patient presenting 6 or more episodes of orofacial herpes infections during the preceding 12-months' period (prior to the study entry),

• Woman of childbearing age under effective contraception,

• Patient reporting a current stable sexual relationship (steady sexual partner during study duration),

• Patient having faculties to understand and respect the constraints of the study,

• Signature of the Informed Consent Form.

Exclusion Criteria:

• Pregnant or breastfeeding woman,

• Patient under immunotherapy (including immunosuppressive treatment) or micro-immunotherapy received during last previous 6 months,

• Patient who had a suppressive antiviral therapy during last month,

• Patient who wishes to continue his/her suppressive antiviral therapy,

• Patient with known lactose intolerance,

• Patient who participated in a clinical study in the previous 3-month period,

• Patient who is not sufficiently motivated to engage in a follow-up period of 12 months, or likely to travel or to move before the end of the study,

• Patient with severe immunodeficiency disease requiring long term treatment (*) or under chemotherapy or radiotherapy or corticoid therapy,

• Patient under listed homeopathic or phytotherapy treatment,

• Patient using or addicted to recreational drugs. (*) important renal or respiratory insufficiency, transplanted or grafted patients HIV/AIDS, terminal cancer.