Overview

Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis

Status:
Completed

Trial end date:
2000-09-01

Target enrollment:

Participant gender:

Summary

OBJECTIVES: I. Compare the efficacy of two doses of folic acid in normalizing plasma total homocysteine concentration in patients with end stage renal disease receiving regular hemodialysis therapy resulting in hyperhomocysteinemia. II. Determine the requirement of co-supplementation with extra pyridoxine (vitamin B6) and cyanocobalamin (vitamin B12) daily in these patients. III. Assess the safety and tolerability of this therapy in these patients.

Phase:

N/A

Details

Lead Sponsor:

Georgetown University

Treatments:

Folic Acid
Hydroxocobalamin
Pyridoxine
Vitamin B 12
Vitamin B Complex