Overview

Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma

Status:
Completed
Trial end date:
2015-05-01
Target enrollment:
0
Participant gender:
All
Summary
The study aim to study whether spinal anesthesia (using: bupivacain, morfin och klonidin) can be better than epidural anesthesia during and after open surgery for renal cell carcinoma. Per- and postoperative pain after spinal anesthesia with klonidin can be reduced and, thus, shorten the hospital stay and rehabilitation of the patients.
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Umeå University
Collaborator:
University Hospital, Umeå
Treatments:
Anesthetics
Bupivacaine
Clonidine
Criteria
Inclusion Criteria:

- all patients in ASA score I - III, planned to be treated with open radical nephrectomy
or nephron-sparing surgery having renal cell carcinoma

Exclusion Criteria:

- patients in ASA score IV-V,

- patients with advanced tumour thrombus in vena cava inferior,

- patients with high risk for bleeding

- patients with previous chronic pain symptoms

- patients having drug abuse

- patients having cognitive deficiencies or dementia disease

- patients with any contraindication of either spinal or epidural anesthesia

- patients younger than 18 years and pregnant woman

- patients having a weight less than 45 kg or weight over 120 kg