Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal

• Status: Completed
• Trial end date: 2020-01-11
• Target enrollment: 0
• Participant gender: All

Summary

This study plans to learn more about whether ibuprofen can reduce pain after removal of a ureteral stent more than a placebo. Some patients experience pain after removal of a ureteral stent. The investigators plan to learn how often this occurs and whether it can be prevented.

The investigators hypothesize that children who have a temporary, indwelling ureteral stent will experience a significantly less post-operative pain if given a non-steroidal anti-inflammatory (NSAID) prior to removal of the ureteral stent when compared to placebo. The investigators hypothesize that the incidence of severe post-stent removal pain is similar to an adult population.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Colorado, Denver
• Collaborator: Children's Hospital Colorado
• Treatments: Ibuprofen

Criteria

Inclusion Criteria:

• ages 4-17

• unilateral ureteral stent placed after ureteropelvic junction obstruction repair or treatment of upper tract urolithiasis

Exclusion Criteria:

• bilateral stents

• undergoing other concomitant procedure at time of planned ureteral stent removal

• indication for stent other than ureteropelvic junction obstruction repair or treatment of upper tract urolithiasis

• pregnant

• developmental delay

• allergy to ibuprofen or non-steroidal anti-inflammatory medication class

• chronic kidney disease

• prior renal transplant

• history of nasal polyps

• history of asthma