Ranitidin Versus Omeprazole in Patients Taking Clopidogrel
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
Previous reports have shown a possible drug interaction between clopidogrel and proton pump
inhibitors (PPI´s), which could result in increased number of adverse cardiovascular events
among patients on dual antiplatelet therapy(DAPT). Because of this, ranitidin has been
proposed as an alternative drug to PPI´s for prophylaxis of gastrointestinal bleeding in
patients who need DAPT. The study´s aim is to test the hypothesis that ranitidin doesn´t have
any influence on clopidogrel pharmacodynamic.