Rapid Sequence Intubation With Rocuronium-Sugammadex Compared With Succinylcholine
Status:
Completed
Trial end date:
2011-02-01
Target enrollment:
Participant gender:
Summary
Rapid sequence intubation is used, when there is an elevated risk of aspiration to the lungs
of stomach content. It is typically used in acute settings that require acute surgery or in
prehospital settings, but also in specific risk patients requiring elective surgery. The
reason for conducting rapid sequence intubation is to minimize the risk of pulmonary
aspiration and at the same time achieve a fast induction of anaesthesia and intubation. Rapid
sequence intubation is a procedure with a high risk of complications in itself. The time
period from induction of anaesthesia to intubation is particularly risky, because the patient
is apneic. This study addresses this problem by investigating, how quickly spontaneous
respiration can be reestablished after a rapid sequence intubation when using
Rocuronium-Sugammadex compared to Succinylcholine. This is a pilot protocol that is intended
to establish a sample size for the full protocol.
Study hypothesis: The time from correct tube placement to spontaneous respiration is shorter
when using Rocuronium/Sugammadex compared to Succinylcholine.