Rapydan Topical Anaesthesia for Arterial Cannulation

• Status: Completed
• Trial end date: 2011-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Arterial catheterization is painful and is associated with patient stress and anxiety. Analgesia is usually provided by subcutaneous injection of local anesthetic. An alternative is topical anaesthesia, such as Rapydan which is a novel topical anesthetic patch containing 70 mg each of lidocaine and tetracaine. We therefore tested the hypothesis that Rapydan patch analgesia is non-inferior to subcutaneous local anesthetic.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Vienna
• Collaborators: Population Health Research Institute; The Cleveland Clinic
• Treatments: Anesthetics; Lidocaine; Tetracaine

Criteria

Inclusion Criteria:

• Patients having elective valve-replacement or coronary artery bypass grafting requiring arterial access before induction of anaesthesia.

Exclusion Criteria:

• analgesic use within 24 hours before surgery

• injury or infection at the planned puncture site

• known allergy to local anesthetics

• drug abuse

• alcoholism or psychiatric disorders

• childbearing potential without adequate birth control

• abnormal Allen's test