Rate Control in Atrial Fibrillation

• Status: Unknown status
• Trial end date: 2017-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the efficacy of metoprolol tartrate compared to carvedilol on heart rate control in patients with atrial fibrillation and a rapid ventricular rate.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Creighton University
• Treatments: Carvedilol; Metoprolol

Criteria

Inclusion Criteria:

• Permanent atrial fibrillation

• Baseline ventricular rate (prior to treatment) > 110 bpm

Exclusion Criteria:

• History of accessory tract re-entry tachycardia

• Ejection fraction < 35% or history of NYHA Class III/IV stage C/D heart failure

• Acute coronary syndrome, percutaneous coronary intervention, or cardiac surgery in the past 2 months

• Child-Pugh class B or C hepatic dysfunction

• Uncontrolled hypertension

• Thyroid disease

• Intolerance to beta-blockers

• History of lung disease resulting in hospitalization in the past year