Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial

• Status: Completed
• Trial end date: 2020-02-20
• Target enrollment: 0
• Participant gender: All

Summary

Rheumatoid Arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, joint tenderness and destruction of synovial joints, leading to severe disability and premature mortality.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Doxycycline; Rheumatoid Factor; Uric Acid

Criteria

Inclusion Criteria:

• Patients included in this study are patients with RA (either newly or previously diagnosed) with their age between 18-50 years old having the same normal range of body mass index

Exclusion Criteria:

1. - The investigators will exclude patients with risk factors for atherosclerosis other than rheumatoid arthritis such as:

• Smoking.

• Obesity.

• Hypertension.

• Diabetes.

• History of renal or liver diseases.

• Corticosteroid therapy. 2- Intercurrent infections as they may interfere with levels of metalloproteinases.

3- Pregnant or lactating females .