Reassessment of Premedication in Surgery

• Status: Completed
• Trial end date: 2013-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test the level of anxiety in patients, the day before surgery (late afternoon) and immediately prior to surgery in 3 parallel groups of patients.

• one receiving placebo before going to sleep (before sleep), the day prior surgery and placebo when awakening (awakening), the day of surgery

• one receiving zopiclone (7.5 mg) before sleep and placebo at awakening

• one receiving placebo before sleep and alprazolam (0.5 mg)at awakening

double blind, randomized controlled study

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Angers
• Treatments: Alprazolam; Zopiclone

Criteria

Inclusion Criteria:

• age 18-65 years old

• elective surgery

• in-hospital night before surgery

Exclusion Criteria:

• myasthenia gravis

• chronic intake of psychotropic drugs

• opiates intake

• severe obstructive sleep apnea

• intracranial hypertension

• morbid obesity

• myasthenia gravis

• acute severe medical disorder

• non health insurance coverage

• protected patients by law

• pregnancy

• non French speaking