Recombinant Human Granulocyte Macrophage Colony Stimulating Factor(rhGM-CSF) Treating Oral Mucositis
Status:
Unknown status
Trial end date:
2014-08-01
Target enrollment:
Participant gender:
Summary
This is a open,randomized phase II trial comparing effectiveness and safety of local use of
rhGM-CSF and Compound Vitamin B12 to Compound Vitamin B12 solution alone treating oral
mucositis in primary nasopharyngeal cancer. The main end point is the incidence of grade II
and less oral mucositis at the end of treatment.The hypothesis of the study is that the local
use of rhGM-CSF and Compound Vitamin B12 can decrease the incidence of grade III and more
oral mucositis at the end of treatment compared to local use of Compound Vitamin B12 alone.
Phase:
Phase 2
Details
Lead Sponsor:
Wei LUO
Treatments:
Hydroxocobalamin Molgramostim Pharmaceutical Solutions Vitamin B 12 Vitamin B Complex Vitamins