Recovery of Muscle Function After Deep Neuromuscular Block by Means of Diaphragm Ultrasonography

• Status: Unknown status
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Diaphragm ultrasonography as a diagnostic tool in order to demonstrate the superiority of Sugammadex vs. AChEI in facilitating post-operative neuromuscular recovery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Florence
• Collaborator: Merck Sharp & Dohme Corp.
• Treatments: Atropine; Fentanyl; Neostigmine; Propofol; Rocuronium; Sevoflurane

Criteria

Inclusion Criteria:

• ASA physical status I-II

• age between 18-80 years old

• dNMB with rocuronium during ear nose and throat (ENT) surgery

Exclusion Criteria:

• Clinical diagnosis of hepatic or renal disease

• Clinical diagnosis of chronic or acute alcoholism

• History of allergy or hypersensitivity to Sugammadex and/or atropine or Neostigmine

• Current medications with CNS effects

• History of neurologic disease

• Diaphragmatic palsy

• Pregnancy or nursing

• History of malignant arrhythmias